Monday, 31 October 2011

The nuclear pore ruptures and becomes markedly bigger

The nuclear pore ruptures and becomes markedly bigger, which enables the viral DNA to enter the cell nucleus more easily. Surprisingly, the cell repairs the defective nuclear pore so that the virus breach in the nucleus does not leave any visible damage in its wake. The viral DNA is smuggled into the nucleus practically without trace, where it can reproduce easily.The researchers used adenoviruses for their study. Adenoviruses cause, among other things, respiratory(呼吸的) or epidemic ocular disease. Until recently, they were thought to be relatively harmless for healthy humans. However, the results of another research group recently demonstrated that a new kind of adenovirus triggered a dreaded zoonotic(动物传染病的) disease, meaning it was transmitted from an animal to humans before spreading from one person to another.